Product Quality Control in Semibatch Reactors Using Midcourse Correction Policies

A practical approach to the control of final product quality in semibatch reactors is proposed. It is based on the use of readily available on-line measurements such as temperatures plus a few off-line analyses obtained from one or more samples taken from the reactor throughout the course of the batch run. These measurements are used either with a theoretically-based model or with simple empirical regression models to predict the final product …