Multiple recurrent genetic events converge on...

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

Abstract

Michael Taylor and colleagues identify copy number aberrations of genes with critical roles in writing, reading, removing and blocking the state of histone lysine methylation, indicating that defective control of the histone code contributes to the pathogenesis of medulloblastoma.

Authors

Northcott PA; Nakahara Y; Wu X; Feuk L; Ellison DW; Croul S; Mack S; Kongkham PN; Peacock J; Dubuc A

Journal

Nature Genetics, Vol. 41, No. 4, pp. 465–472

Publisher

Springer Nature

Publication Date

April 1, 2009

DOI

10.1038/ng.336

ISSN

1061-4036

Associated Experts

Boleslaw Lach

Professor Emeritus, Faculty of Health Sciences

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