Polymer‐grafted starch microparticles for oral and nasal immunization

Microparticle delivery systems for oral vaccine administration are receiving considerable attention. A novel silicone polymer-grafted starch microparticle system was developed that is efficacious both orally and intranasally. Unlike most other microparticle systems, this novel system does not appear to retard the release of antigen or to protect antigen from degradation. The results indicate that a unique physiochemical relationship occurs …