Journal article
Immunoglobulin E mediated membrane conductance changes in rat basophilic leukemia cells
Abstract
Electrophysiological effects of anaphylactic stimulation of rat basophilic leukemia cells (RBL-2H3) were studied using conventional microelectrodes. Stimulation of passively sensitized cells by anti-immunoglobulin E resulted in hyperpolarization followed by depolarization. These changes in membrane polarization were associated with a decrease in input membrane resistance. No effect of anaphylactic stimulation was seen in Ca2+-free solution or …
Authors
Barajas-López C; Huizinga JD
Journal
Canadian Journal of Physiology and Pharmacology, Vol. 66, No. 3, pp. 328–331
Publisher
Canadian Science Publishing
Publication Date
March 1, 1988
DOI
10.1139/y88-056
ISSN
0008-4212