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Imaging interactions of cationic antimicrobial...
Journal article

Imaging interactions of cationic antimicrobial peptides with model lipid monolayers using X-ray spectromicroscopy

Abstract

The interaction of antimicrobial peptide anoplin with 1,2-dipalmitoyl-sn-glycero-3-[phospho-rac-(1-glycerol)] lipid monolayers was imaged with atomic force microscopy, scanning transmission X-ray microscopy, and X-ray photoemission electron microscopy. X-ray absorption spectromicroscopy of the surface revealed the domains of the phase-segregated surface to be composed of 98(±5)% lipid while the matrix consisted of a ~50:50 lipid-peptide …

Authors

Leung BO; Hitchcock AP; Won A; Ianoul A; Scholl A

Journal

European Biophysics Journal, Vol. 40, No. 6, pp. 805–810

Publisher

Springer Nature

Publication Date

6 2011

DOI

10.1007/s00249-011-0690-7

ISSN

0175-7571