Journal article
A developmental characterization of mesolimbocortical serotonergic gene expression changes following early immune challenge
Abstract
An immunogenic challenge during early postnatal development leads to long-term changes in behavioural and physiological measures reflecting enhanced emotionality and anxiety. Altered CNS serotonin (5-HT) signalling during the third postnatal week is thought to modify the developing neurocircuitry governing anxiety-like behaviour. Changes in 5-HT signalling during this time window may underlie increased emotionality reported in early immune …
Authors
Sidor MM; Amath A; MacQueen G; Foster JA
Journal
Neuroscience, Vol. 171, No. 3, pp. 734–746
Publisher
Elsevier
Publication Date
December 2010
DOI
10.1016/j.neuroscience.2010.08.060
ISSN
0306-4522