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Application of the Laguerre Deconvolution Method...
Journal article

Application of the Laguerre Deconvolution Method for Time-Resolved Fluorescence Spectroscopy to the Characterization of Atherosclerotic Plaques

Abstract

This study investigates the ability of time-resolved laser-induced fluorescence spectroscopy (TR-LIFS) to detect inflammation in atherosclerotic lesion, a key feature of plaque vulnerability. A total of 348 TR-LIFS measurements were taken from carotid plaques of 30 patients, and subsequently analyzed using the Laguerre deconvolution technique. The investigated spots were classified as Early, Fibrotic/Calcified or Inflamed lesions. A stepwise …

Authors

Jo JA; Fang Q; Papaioannou T; Qiao JH; Fishbein MC; Beseth B; Dorafshar AH; Reil T; Baker D; Freischlag J

Journal

Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Vol. 2005, , pp. 6559–6562

Publisher

Institute of Electrical and Electronics Engineers (IEEE)

Publication Date

2005

DOI

10.1109/iembs.2005.1616003

ISSN

1557-170X