Journal article
Direct and delayed X‐ray‐induced DNA damage in male mouse germ cells
Abstract
Sperm DNA integrity is essential for the accurate transmission of paternal genetic information. Various stages of spermatogenesis are characterized by large differences in radiosensitivity. Differentiating spermatogonia are susceptible to radiation-induced cell killing, but some of them can repair DNA damage and progress through differentiation. In this study, we applied the neutral comet assay, immunodetection of phosphorylated H2AX (γ-H2AX) …
Authors
Cordelli E; Eleuteri P; Grollino MG; Benassi B; Blandino G; Bartoleschi C; Pardini MC; Di Caprio EV; Spanò M; Pacchierotti F
Journal
Environmental and Molecular Mutagenesis, Vol. 53, No. 6, pp. 429–439
Publisher
Wiley
Publication Date
7 2012
DOI
10.1002/em.21703
ISSN
0893-6692