A novel Myb‐related protein involved in transcriptional activation of encystation genes in Giardia lamblia

Abstract

Giardia lamblia is an important human intestinal parasite that survives outside of the host by differentiation of trophozoites into infectious cysts. Transcriptional regulation is key for encystation gene expression, but the mechanisms are unknown. Giardia genome database searches identified a myb-like gene (gmyb2) whose expression increased during encystation. Epitope-tagged gMyb2 localized to both nuclei. DNA binding and mutation analysis …

Authors

Sun C; Palm D; McArthur AG; Svärd SG; Gillin FD

Journal

Molecular Microbiology, Vol. 46, No. 4, pp. 971–984

Publisher

Wiley

Publication Date

November 2002

DOI

10.1046/j.1365-2958.2002.03233.x

ISSN

0950-382X

Associated Experts

Andrew McArthur

Professor, Faculty of Health Sciences

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