Journal article
Evolution of Eukaryotic Transcription: Insights From the Genome of Giardia lamblia
Abstract
The Giardia lamblia genome sequencing project affords us a unique opportunity to conduct comparative analyses of core cellular systems between early and late-diverging eukaryotes on a genome-wide scale. We report a survey to identify canonical transcription components in Giardia, focusing on RNA polymerase (RNAP) subunits and transcription-initiation factors. Our survey revealed that Giardia contains homologs to 21 of the 28 polypeptides …
Authors
Best AA; Morrison HG; McArthur AG; Sogin ML; Olsen GJ
Journal
Genome Research, Vol. 14, No. 8, pp. 1537–1547
Publisher
Cold Spring Harbor Laboratory
Publication Date
August 2004
DOI
10.1101/gr.2256604
ISSN
1088-9051