Journal article
Non-neutral evolution and reciprocal monophyly of two expressed Mhc class II B genes in Leach’s storm-petrel
Abstract
The major histocompatibility complex (Mhc) is subject to pathogen-mediated balancing selection and can link natural selection with mate choice. We characterized two Mhc class II B loci in Leach’s storm-petrel, Oceanodroma leucorhoa, focusing on exon 2 which encodes the portion of the protein that binds pathogen peptides. We amplified and sequenced exon 2 with locus-specific nested PCR and Illumina MiSeq using individually barcoded primers. …
Authors
Dearborn DC; Gager AB; Gilmour ME; McArthur AG; Hinerfeld DA; Mauck RA
Journal
Immunogenetics, Vol. 67, No. 2, pp. 111–123
Publisher
Springer Nature
Publication Date
February 2015
DOI
10.1007/s00251-014-0813-2
ISSN
0093-7711
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Amino Acid SequenceAnimalsAvian ProteinsBase SequenceBirdsDNAEvolution, MolecularExonsFemaleGene ConversionGene DuplicationGenes, MHC Class IIGenetic VariationHistocompatibility Antigens Class IIMaleMolecular Sequence DataPhylogenySelection, GeneticSequence Homology, Amino AcidSequence Homology, Nucleic Acid