Journal article
Differential Sensitivity of Mouse Mononuclear Phagocytes to CSF-1 and LPS: The Potentialin VivoRelevance of Enhanced IL-6 Gene Expression
Abstract
In this report, we compared the responsiveness of subpopulations of mononuclear phagocytes (MNP) to the actions of the monocyte-macrophage colony-stimulating factor (CSF-1) and lipopolysaccharide (LPS), as measured by the expression of the IL-6 (Il6) gene. It was seen that neither monocytes nor elicited peritoneal macrophages (PMphi) responded directly to CSF-1 compared with resident PMphi that were induced to express high levels of Il6 mRNA …
Authors
Kamdar SJ; Chapoval AI; Phelps J; Fuller JA; Evans R
Journal
Cellular Immunology, Vol. 174, No. 2, pp. 165–172
Publisher
Elsevier
Publication Date
12 1996
DOI
10.1006/cimm.1996.0306
ISSN
0008-8749