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Combination antibiotic susceptibility testing to...
Journal article

Combination antibiotic susceptibility testing to treat exacerbations of cystic fibrosis associated with multiresistant bacteria: a randomised, double-blind, controlled clinical trial

Abstract

BACKGROUND: We did a randomised, double-blind, controlled clinical trial to prospectively assess whether use of combination antibiotic susceptibility testing improved clinical outcomes in patients with acute pulmonary exacerbations of cystic fibrosis who were infected with multiresistant bacteria. METHODS: 251 patients with cystic fibrosis who were chronically infected with multiresistant gram negative bacteria gave sputum at 3-month intervals …

Authors

Aaron SD; Vandemheen KL; Ferris W; Fergusson D; Tullis E; Haase D; Berthiaume Y; Brown N; Wilcox P; Yozghatlian V

Journal

The Lancet, Vol. 366, No. 9484, pp. 463–471

Publisher

Elsevier

Publication Date

August 2005

DOI

10.1016/s0140-6736(05)67060-2

ISSN

0140-6736