Journal article
Therapeutic Effect of Angiostatin Gene Transfer in a Murine Model of Endometriosis
Abstract
Endometriosis, the growth of ectopic endometrial tissue, is a chronic recurrent disease affecting 10% of the female population causing dyspareunia, pelvic pain, dysmenorrhea, and infertility. Suppression of ovarian activity is the cornerstone of medical therapy with limited benefit and severe adverse effects. Angiogenesis plays a major role in the development of endometriosis suggesting that anti-angiogenic therapy would offer a new therapeutic …
Authors
Dabrosin C; Gyorffy S; Margetts P; Ross C; Gauldie J
Journal
American Journal Of Pathology, Vol. 161, No. 3, pp. 909–918
Publisher
Elsevier
Publication Date
September 2002
DOI
10.1016/s0002-9440(10)64251-4
ISSN
0002-9440