Oral Salt and Water versus Intravenous Saline for the Prevention of Acute Kidney Injury following Contrast-Enhanced Computed Tomography: Study Protocol for a Pilot Randomized Trial

BACKGROUND: Although intravenous saline is the accepted prophylactic measure for the prevention of contrast- induced acute kidney injury, the oral route could offer an equivalent, practical, and cost saving approach. A systematic review of randomized trials that compared oral versus intravenous volume expansion for the prevention of radiocontrast-induced nephropathy in patients receiving arterial contrast reported no significant difference in …