Comparison of published orthopaedic trauma trials following registration in Clinicaltrials.gov

BackgroundAfter the Food and Drug Administration Modernization Act of 1997, the registration of all clinical trials became mandatory prior to publication. Our primary objective was to determine publication rates for orthopaedic trauma trials registered with ClinicalTrials.gov. We further evaluated methodological consistency between registration and publication.MethodsWe searched Clinical Trials.gov for all trials related to orthopaedic trauma. …