Journal article
The fragility of statistically significant findings from randomized trials in spine surgery: a systematic survey
Abstract
BACKGROUND CONTEXT: Randomized controlled trials (RCTs) are the most trustworthy source for evaluating treatment effects, but RCTs of spine surgery interventions often produce discordant results. The Fragility Index is a novel metric to inform about the robustness of statistically significant results.
PURPOSE: The aim was to determine the robustness of statistically significant results from RCTs of spine surgery interventions.
Authors
Evaniew N; Files C; Smith C; Bhandari M; Ghert M; Walsh M; Devereaux PJ; Guyatt G
Journal
The Spine Journal, Vol. 15, No. 10, pp. 2188–2197
Publisher
Elsevier
Publication Date
October 2015
DOI
10.1016/j.spinee.2015.06.004
ISSN
1529-9430