Journal article
A genome-wide scan for common alleles affecting risk for autism
Abstract
Although autism spectrum disorders (ASDs) have a substantial genetic basis, most of the known genetic risk has been traced to rare variants, principally copy number variants (CNVs). To identify common risk variation, the Autism Genome Project (AGP) Consortium genotyped 1558 rigorously defined ASD families for 1 million single-nucleotide polymorphisms (SNPs) and analyzed these SNP genotypes for association with ASD. In one of four primary …
Authors
Anney R; Klei L; Pinto D; Regan R; Conroy J; Magalhaes TR; Correia C; Abrahams BS; Sykes N; Pagnamenta AT
Journal
Human Molecular Genetics, Vol. 19, No. 20, pp. 4072–4082
Publisher
Oxford University Press (OUP)
Publication Date
October 15, 2010
DOI
10.1093/hmg/ddq307
ISSN
0964-6906