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Individual common variants exert weak effects on...
Journal article

Individual common variants exert weak effects on the risk for autism spectrum disorders

Abstract

While it is apparent that rare variation can play an important role in the genetic architecture of autism spectrum disorders (ASDs), the contribution of common variation to the risk of developing ASD is less clear. To produce a more comprehensive picture, we report Stage 2 of the Autism Genome Project genome-wide association study, adding 1301 ASD families and bringing the total to 2705 families analysed (Stages 1 and 2). In addition to …

Authors

Anney R; Klei L; Pinto D; Almeida J; Bacchelli E; Baird G; Bolshakova N; Bölte S; Bolton PF; Bourgeron T

Journal

Human Molecular Genetics, Vol. 21, No. 21, pp. 4781–4792

Publisher

Oxford University Press (OUP)

Publication Date

November 1, 2012

DOI

10.1093/hmg/dds301

ISSN

0964-6906