Journal article
Conducting Genetic Epidemiology Studies of Autism Spectrum Disorders: Issues in Matching
Abstract
The objective of this review is to clarify the role of matching in family genetic studies of autism as a way of defining endophenotypes for linkage analysis. The concept of a confounding variable is reviewed and the importance of considering these in family studies of three endophenotypes in autism are considered: cognitive/language impairments, psychiatric disorders, and autistic-like traits. The importance of matching in infant sibling …
Authors
Szatmari P; Zwaigenbaum L; Bryson S
Journal
Journal of Autism and Developmental Disorders, Vol. 34, No. 1, pp. 49–57
Publisher
Springer Nature
Publication Date
February 2004
DOI
10.1023/b:jadd.0000018074.74369.cd
ISSN
0162-3257