Journal article
CD23-Mediated IgE Transport Across Human Intestinal Epithelium: Inhibition by Blocking Sites of Translation or Binding
Abstract
BACKGROUND & AIMS: In previous studies in rodent models of food allergy, we identified that sensitization induces expression of CD23 on intestinal epithelial cells and results in enhanced IgE-dependent transepithelial antigen uptake; further studies in CD23-/- mice provided evidence that CD23 is involved in protected transport of antigen into the body. Little information exists in humans on receptor-mediated immunoglobulin (Ig)E transport …
Authors
Tu Y; Salim S; Bourgeois J; Di Leo V; Irvine EJ; Marshall JK; Perdue MH
Journal
Gastroenterology, Vol. 129, No. 3, pp. 928–940
Publisher
Elsevier
Publication Date
September 2005
DOI
10.1053/j.gastro.2005.06.014
ISSN
0016-5085