Journal article
Inflammatory infratentorial progressive multifocal leukoencephalopathy in a patient with rheumatoid arthritis
Abstract
An 84-year-old man with rheumatoid arthritis (RA) treated with methotrexate, developed progressive confusion and cerebellar symptoms, and died approximately 2 months later. Neuropathological examination revealed progressive multifocal leukoencephalopathy (PML) involving the cerebellum and brainstem. The affected tissues displayed intense infiltrations by CD8+ T-cells and microglia. JC virus was localized in oligodendroglia and cerebellar …
Authors
Lach B; Connolly B; Wüthrich C; Koralnik IJ
Journal
Neuropathology, Vol. 34, No. 1, pp. 39–44
Publisher
Wiley
Publication Date
February 2014
DOI
10.1111/neup.12045
ISSN
0919-6544