Journal article
Combined Metabolomic and Proteomic Analysis of Human Atrial Fibrillation
Abstract
OBJECTIVES: We sought to decipher metabolic processes servicing the increased energy demand during persistent atrial fibrillation (AF) and to ascertain whether metabolic derangements might instigate this arrhythmia.
BACKGROUND: Whereas electrical, structural, and contractile remodeling processes are well-recognized contributors to the self-perpetuating nature of AF, the impact of cardiac metabolism upon the persistence/initiation of this …
Authors
Mayr M; Yusuf S; Weir G; Chung Y-L; Mayr U; Yin X; Ladroue C; Madhu B; Roberts N; De Souza A
Journal
Journal of the American College of Cardiology, Vol. 51, No. 5, pp. 585–594
Publisher
Elsevier
Publication Date
February 2008
DOI
10.1016/j.jacc.2007.09.055
ISSN
0735-1097