Journal article
Age-dependent immune responses and immune protection after avian coronavirus vaccination
Abstract
Infectious bronchitis virus (IBV) is an endemic disease of chickens and a major contributor to economic losses for the poultry industry despite vaccination. Recent observations indicated that chicks may have an immature immune system immediately after hatching when vaccinated for IBV. Therefore we hypothesized that early IBV vaccination will generate an immature, poorly protective IBV-specific immune response contributing to immune escape and …
Authors
van Ginkel FW; Padgett J; Martinez-Romero G; Miller MS; Joiner KS; Gulley SL
Journal
Vaccine, Vol. 33, No. 23, pp. 2655–2661
Publisher
Elsevier
Publication Date
May 2015
DOI
10.1016/j.vaccine.2015.04.026
ISSN
0264-410X