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A randomized trial to assess the efficacy of...
Journal article

A randomized trial to assess the efficacy of surgery in addition to radiotherapy in patients with a single cerebral metastasis

Abstract

BACKGROUND: Cerebral metastasis is a common oncologic problem that occurs in 15-30% of cancer patients; approximately half such metastases are single. Previous retrospective studies and two randomized trials reported that the addition of surgical extirpation prior to radiation therapy increased survival, neurologic function, and quality of life compared with radiation alone in patients with a single brain metastasis. METHODS: A randomized …

Authors

Mintz AH; Kestle J; Rathbone MP; Gaspar L; Hugenholtz H; Fisher B; Duncan G; Skingley P; Foster G; Levine M

Journal

Cancer, Vol. 78, No. 7, pp. 1470–1476

Publisher

Wiley

Publication Date

October 1, 1996

DOI

10.1002/(sici)1097-0142(19961001)78:7<1470::aid-cncr14>3.0.co;2-x

ISSN

1097-0142