Journal article
Vardenafil and Weaning from Inhaled Nitric Oxide: Effect on Pulmonary Hypertension in ARDS
Abstract
We report a 66-year-old patient with refractory pulmonary hypertension secondary to ARDS who was being treated with inhaled nitric oxide. Enteral vardenafil (phosphodiesterase-5 inhibitor) was tried at two different doses (10 mg and 5 mg), in order to wean the patient from nitric oxide. The higher dose decreased pulmonary pressure but caused systemic hypotension and the drug was discontinued. Subsequently, a 5 mg dose of vardenafil decreased …
Authors
Giacomini M; Borotto E; Bosottl L; Denkewitz T; Reali-Forster C; Carlucci P; Centanni S; Mantero A; Iapichino G
Journal
Anaesthesia and Intensive Care, Vol. 35, No. 1, pp. 91–93
Publisher
SAGE Publications
Publication Date
February 2007
DOI
10.1177/0310057x0703500113
ISSN
0310-057X