Journal article
Protection Induced by Simultaneous Subcutaneous and Endobronchial Vaccination with BCG/BCG and BCG/Adenovirus Expressing Antigen 85A against Mycobacterium bovis in Cattle
Abstract
The incidence of bovine tuberculosis (bTB) in the GB has been increasing since the 1980s. Immunisation, alongside current control measures, has been proposed as a sustainable measure to control bTB. Immunisation with Mycobacterium bovis bacillus Calmette-Guerin (BCG) has been shown to protect against bTB. Furthermore, much experimental data indicates that pulmonary local immunity is important for protection against respiratory infections …
Authors
Dean GS; Clifford D; Whelan AO; Tchilian EZ; Beverley PCL; Salguero FJ; Xing Z; Vordermeier HM; Villarreal-Ramos B
Journal
PLOS ONE, Vol. 10, No. 11,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pone.0142270
ISSN
1932-6203