Journal article
Intrapulmonary, Adenovirus-Mediated Overexpression of KARAP/DAP12 Enhances Fungal Clearance during Invasive Aspergillosis
Abstract
Herein, we report that the intrapulmonary delivery of an adenovirus vector expressing KARAP/DAP12, an adaptor protein expressed in granulocytes and mononuclear cells, enhanced fungal clearance during experimental invasive pulmonary aspergillosis in neutropenic mice.
Authors
Carpenter KJ; Buckland KF; Xing Z; Hogaboam CM
Journal
Infection and Immunity, Vol. 73, No. 12, pp. 8402–8406
Publisher
American Society for Microbiology
Publication Date
December 2005
DOI
10.1128/iai.73.12.8402-8406.2005
ISSN
0019-9567