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Changes in Bone Marrow Inflammatory Cell...
Journal article

Changes in Bone Marrow Inflammatory Cell Progenitors after Inhaled Allergen in Asthmatic Subjects

Abstract

Increases in inflammatory cell progenitors, particularly eosinophil/basophil colony-forming cells (Eo/B-CFU), occur in peripheral blood after allergen provocation. The role of bone marrow (BM) in these reactions is unclear. We examined the effect of allergen challenge on human bone marrow progenitor cell growth. Fifteen asthmatic subjects, eight dual responders (DR) and seven isolated early responders (IER), were challenged with inhaled …

Authors

WOOD LJ; INMAN MD; WATSON RM; FOLEY R; DENBURG JA; O'BYRNE PM

Journal

American Journal of Respiratory and Critical Care Medicine, Vol. 157, No. 1, pp. 99–105

Publisher

Oxford University Press (OUP)

Publication Date

January 1, 1998

DOI

10.1164/ajrccm.157.1.9704125

ISSN

1073-449X