The role of the bone marrow in allergy and asthma

The above studies have begun to address the fundamental question of the mechanisms of bone marrow involvement and response to allergen challenge in allergic asthmatics. Further studies in this area should complement our investigations in human asthma--which suggest that a particular bias toward differentiation of Eo-Baso progenitors characterizes the atopic state--as well as our findings in the dog model of allergen-induced airway …