Journal article
Ryanodine receptors decant internal Ca2+ store in human and bovine airway smooth muscle
Abstract
Several putative roles for ryanodine receptors (RyR) were investigated in human and bovine airway smooth muscle. Changes in intracellular Ca2+ concentration ([Ca2+]i) and membrane current were investigated in single cells by confocal fluorimetry and patch-clamp electrophysiology, respectively, whereas mechanical activity was monitored in intact strips with force transducers. RyR released Ca2+ from the sarcoplasmic reticulum in a ryanodine- and …
Authors
Tazzeo T; Zhang Y; Keshavjee S; Janssen LJ
Journal
European Respiratory Journal, Vol. 32, No. 2, pp. 275–284
Publisher
European Respiratory Society (ERS)
Publication Date
August 2008
DOI
10.1183/09031936.00167007
ISSN
0903-1936