Journal article
Analyzing Oncology Clinical Trial Data Using the Q-TWiST Method: Clinical Importance and Sources for Health State Preference Data*
Abstract
Purpose: The Quality-adjusted Time Without Symptoms of disease and Toxicity (Q-TWiST) analysis method is frequently applied to evaluating outcomes in cancer clinical trials, but there is little information on what constitutes a clinically important difference (CID). We reviewed the Q-TWiST, health-related quality of life (HRQL) and utility measurement literature to develop recommendations for CID for the Q-TWiST. We also provide recommendations …
Authors
Revicki DA; Feeny D; Hunt TL; Cole BF
Journal
Quality of Life Research, Vol. 15, No. 3, pp. 411–423
Publisher
Springer Nature
Publication Date
4 2006
DOI
10.1007/s11136-005-1579-7
ISSN
0962-9343