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Journal article

Systemic Therapy in Patients With Metastatic Castration-Resistant Prostate Cancer: ASCO Living Guideline, Version 2026.1.

Abstract

Living guidelines are developed for selected topic areas with rapidly evolving evidence that drives frequent change in recommended clinical practice. Living guidelines are updated on a regular schedule by a standing expert panel that systematically reviews the health literature on a continuous basis, as described in the ASCO Guidelines Methodology Manual. ASCO Living Guidelines follow the ASCO Conflict of Interest Policy Implementation for Clinical Practice Guidelines. Living Guidelines and updates are not intended to substitute for independent professional judgment of the treating clinician and do not account for individual variation among patients. See appendix for disclaimers and other important information (Appendix 1 and Appendix 2). Updates are published regularly and can be found at www.asco.org/genitourinary-cancer-guidelines.

Authors

Taplin M-E; Riaz IB; Rumble RB; Naqvi SAA; Hope TA; Dias MF; He H; Hotte SJ; Emamekhoo H; Murad MH

Journal

Journal of Clinical Oncology, , ,

Publisher

American Society of Clinical Oncology (ASCO)

Publication Date

January 20, 2026

DOI

10.1200/jco-25-02693

ISSN

0732-183X

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