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Macrolide Resistance and P1 Cytadhesin Genotyping...
Journal article

Macrolide Resistance and P1 Cytadhesin Genotyping of Mycoplasma pneumoniae during Outbreak, Canada, 2024–2025 - Volume 31, Number 12—December 2025 - Emerging Infectious Diseases journal - CDC

Abstract

We investigated macrolide resistance and P1 genotypes of Mycoplasma pneumoniae during the 2024-2025 outbreak in Hamilton, Ontario, Canada. Macrolide resistance remained stable at ≈10%-20%, but significant shifts in P1 genotype distribution and resistance rates in P1 types occurred, indicating notable changes in M. pneumoniae molecular epidemiology in Ontario since 2011-2012.

Authors

Fatima Z; Jayaratne P; Arrabi A; Rutherford C; Leto D; Smieja M; Hasan MR

Journal

Emerging Infectious Diseases, Vol. 31, No. 12, pp. 2316–2319

Publisher

Centers for Disease Control and Prevention (CDC)

Publication Date

December 1, 2025

DOI

10.3201/eid3112.250872

ISSN

1080-6040

Associated Experts

Marek Smieja

Professor, Faculty of Health Sciences
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Labels

Fields of Research (FoR)

3207 Medical Microbiology32 Biomedical and Clinical Sciences3202 Clinical sciences4202 Epidemiology4203 Health services and systems

Sustainable Development Goals (SDG)

3 Good Health and Well Being

Medical Subject Headings (MeSH)

Mycoplasma pneumoniaeMacrolidesPneumonia, MycoplasmaHumansDrug Resistance, BacterialDisease OutbreaksGenotypeAnti-Bacterial AgentsOntarioMicrobial Sensitivity TestsBacterial ProteinsAdhesins, Bacterial
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