Comparison of Yield and Complications between Different Types of Pediatric Renal Biopsy Devices: A Retrospective Review

Abstract Objective: The objective of this study was to perform a retrospective review comparing the yield and complications between a side slot cutting needle (SSCN) device and Franseen-type full circumference coring needle (FFCCN) devices and investigate our hypothesis that the latter device would demonstrate both greater yield and increased complications owing to its mechanism. Materials and Methods: For 99 patients, 112 pediatric kidney biopsies were performed by interventional radiologists with real-time ultrasound guidance between 2017 and 2021. A total of 68 and 44 biopsies were completed using the SSCN and FFCCN devices, respectively, with two biopsies completed using both devices. The mean age, weight, and body mass index were 11.5 years, 46.09 kg, and 21.58 kg/m 2 (standard deviation 5). Fifty-seven biopsies were performed on female patients. Patient demographics, blood count, yield, and complications were extracted and compared using t -tests and Chi-square tests. Results: A hemoglobin (Hb) drop was the most common complication (67.86%). The incidence of hematuria and Hb drop >15 g/L were higher in the FFCCN group, P = 0.017 and P = 0.032. The overall mean number of cores and the mean amount of Hb drop in transplant kidney biopsies were higher in the SSCN group, P = 0.033 and P = 0.038, respectively. Conclusion: This is the first study to compare these biopsy devices and report on the performance of the FFCCN device. These findings should be considered when evaluating the choice of renal biopsy device.