Quality of life among patients using long-term oxygen therapy for chronic respiratory failure: A prospective observational study

Background: India has a significant burden of chronic respiratory diseases, many of which require long-term oxygen therapy (LTOT) for respiratory failure. Previous studies have shown poor compliance with LTOT, but data on quality of life (QOL) in patients receiving LTOT is limited. Methodology: This was a prospective observational study conducted at a tertiary care center. 56 patients with chronic respiratory failure who were prescribed LTOT were followed up for 6 months, and their QOL was assessed and compared to baseline. Results: Chronic obstructive pulmonary disease was the most common diagnosis (64%), followed by obstructive sleep apnea–obesity hypoventilation syndrome overlap (25%) and interstitial lung disease (20%). Most (77%) of the patients preferred getting an oxygen concentrator on a monthly rental basis, rather than purchasing one. LTOT compliance at 6 months was 44.4%, with reasons for discontinuation including financial constraints (31%), feeling better (28%), and doctor’s advice (24%). There was statistically significant improvement in QOL for patients who continued using oxygen at 6 months. Conclusion: LTOT improves QOL in patients with chronic respiratory diseases, irrespective of the hours of usage.