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Cu(II)-baicalein enhance paracrine effect and...
Journal article

Cu(II)-baicalein enhance paracrine effect and regenerative function of stem cells in patients with diabetes

Abstract

The development of engineered or modified autologous stem cells is an effective strategy to improve the efficacy of stem cell therapy. In this study, the stemness and functionality of adipose stem cells derived from type 1 diabetic donors (T1DM-ASC) were enhanced by treatment with Cu(II)-baicalein microflowers (Cu-MON). After treatment with Cu-MON, T1DM-ASC showed enhanced expression of the genes involved in the cytokine-cytokine receptor …

Authors

Liu K; Li R; Wang S; Fu X; Zhu N; Liang X; Li H; Wang X; Wang L; Li Y

Journal

Bioactive Materials, Vol. 36, , pp. 455–473

Publisher

Elsevier

Publication Date

6 2024

DOI

10.1016/j.bioactmat.2024.03.013

ISSN

2097-1192