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Antigen and molecular testing using one swab:...
Journal article

Antigen and molecular testing using one swab: Lessons learned from a COVID-19 project

Abstract

Rapid SARS-CoV-2 detection is essential in limiting transmission. We evaluated the performance of RT-PCR on the same nasopharyngeal swab used for Panbio antigen testing. High concordance with standard PCR and improved case detection-including asymptomatic infections-demonstrates this one-swab-two-test strategy enhances diagnostic yield while reducing patient discomfort and resource burden.

Authors

Gilchrist J; Smieja N; Marttala S; Waters K; Bulir D; Hasan MR; Smieja M

Journal

Diagnostic Microbiology and Infectious Disease, Vol. 114, No. 2,

Publisher

Elsevier

Publication Date

February 1, 2026

DOI

10.1016/j.diagmicrobio.2025.117188

ISSN

0732-8893

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