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Pursuing Reduction in Fatigue After COVID-19 via...
Journal article

Pursuing Reduction in Fatigue After COVID-19 via Exercise and Rehabilitation (PREFACER): a protocol for a randomised feasibility trial

Abstract

INTRODUCTION: Over 777 million COVID-19 infections have occurred globally, with data suggesting that 10%-20% of those infected develop Long COVID. Fatigue is one of the most common and disabling symptoms of Long COVID. We aim to assess the feasibility and safety of a new, remotely delivered, multimodal rehabilitation intervention, paced to prevent post-exertional malaise (PEM), to support the conduct of a future, definitive randomised trial.

Authors

Billias N; Pouliopoulou DV; Lawson A; D’Alessandro V; Bryant DM; Peters S; Rushton AB; Miller E; Brunton L; McGuire S

Journal

BMJ Open, Vol. 15, No. 11,

Publisher

BMJ

Publication Date

11 2025

DOI

10.1136/bmjopen-2025-102112

ISSN

2044-6055