Bioactive metabolites in Hypsizygus marmoreus spent substrate enhanced Pleurotus ostreatus growth

Abstract

The rapid accumulation of spent mushroom substrate (SMS) presents a critical environmental challenge globally, but efficient and cost-effective recycling approaches remain limited. Here, to advance valorization of SMS, a proof-of-concept study was conducted in which Hypsizygus marmoreus SMS (HmSMS) was recycled in the cultivation of Pleurotus ostreatus. Impacts of the HmSMS-derived bioactive metabolites were further examined systematically. …