Human milk components interact with infant genomics to modulate gut microbiota, childhood asthma and atopy

Summary The benefits of breastfeeding are well established; however, the mechanisms by which human milk components (HMCs) impact children’s long-term health remain poorly understood. We leveraged datasets from the CHILD Cohort Study to explore how exposure to variable HMCs— including oligosaccharides (HMOs), fatty acids (HMFAs), and microbiota (HMM)—may influence infants’ gut microbiota and risk of childhood asthma and atopy. We identified …