Flagellinolysin: bacterial flagellar metallopeptidase

Flagellins are polymeric proteins that assemble to form the extracellular filaments of bacterial flagella. Flagellins have a common domain architecture consisting of an N-terminal and C-terminal domains that assemble the core filament and a hypervariable central region that is surface-exposed. Flagellinolysin is a unique variant of bacterial flagellin that possesses a metallopeptidase domain in the hypervariable region, resulting in …