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Role of miR-21-5p in the pathogenesis of abdominal...
Journal article

Role of miR-21-5p in the pathogenesis of abdominal aortic aneurysm regarding the Th17 pathway

Abstract

Background and aims: The interplay between Th17-related immune activity and miRNA-driven regulation in abdominal aortic aneurysm (AAA) pathogenesis remains poorly understood. In this prospective study, we aimed to assess the potential role of miR-21-5p corresponding to the Th17 pathway disturbances in the development of AAA. Methods: Biological samples were collected from patients with true infrarenal AAA, undergoing elective open abdominal …

Authors

Studzińska D; Lichołai S; Polok K; Plutecka H; Kica P; Grazda P; Chwała M; Sanak M; Szczeklik W

Journal

IJC Heart & Vasculature, Vol. 61, ,

Publisher

Elsevier

Publication Date

December 2025

DOI

10.1016/j.ijcha.2025.101821

ISSN

2214-7632