Experts has a new look! Let us know what you think of the updates.

Provide feedback
Home
Scholarly Works
Considerations for Treating Generalized Pustular...
Journal article

Considerations for Treating Generalized Pustular Psoriasis (GPP): A Narrative Review

Abstract

Generalized pustular psoriasis (GPP) is a rare, chronic dermatological condition characterized by widespread pustulation that may be associated with other cutaneous and systemic manifestations. If left untreated, it may be life-threatening. Therapies developed for plaque psoriasis have been used to treat GPP with limited efficacy; however, these therapies do not target the interleukin (IL)-36 pathway, which is the most common pathway implicated …

Authors

Lynde CW; Prajapati VH; Gooderham MJ; Hong HC-H; Kirchhof MG; Lansang P; Ringuet J; Turchin I; Vender R; Yeung J

Journal

Dermatology and Therapy, , , pp. 1–19

Publisher

Springer Nature

Publication Date

October 9, 2025

DOI

10.1007/s13555-025-01535-7

ISSN

2193-8210