Supplementary Figures from The Germline and...

Supplementary Figures from The Germline and Somatic Origins of Prostate Cancer Heterogeneity

Abstract

<p>Supplementary Figures & Figure Legends. Supplementary Figure 1 | Cohort Structure and Analysis. Supplementary Figure 2 | CNA Evolution & Transcriptomic Effects. Supplementary Figure 3 | Properties of Driver Mutations. Supplementary Figure 4 | Pathway & Signature Analysis of Driver Genes. Supplementary Figure 5 | Patterns of Mutational Drivers. Supplementary Figure 6 | Molecular Correlates of Clinical Behavior. Supplementary Figure 7 | Heterogeneity of Driver-Clinical Associations. Supplementary Figure 8 | Cohort Characteristics and Risk dQTL Replication. Supplementary Figure 9 | Local dQTLs Discovery. Supplementary Figure 10 | Replication of dQTLs. Supplementary Figure 11 | Enrichment of Sub-threshold dQTLs. Supplementary Figure 12 | Molecular Characterization of dQTLs. Supplementary Figure 13 | Association of dQTL Risk SNPs with eQTL and IMS. Supplementary Figure 14 | Clinical Characterization of dQTLs.</p>

Authors

Yamaguchi TN; Houlahan KE; Zhu H; Kurganovs N; Livingstone J; Fox NS; Yuan J; Sietsma Penington J; Jung C-H; Schwarz T

Publication Date

May 2, 2025

DOI

10.1158/2159-8290.28918306

Associated Experts

Katie Houlahan

Assistant Professor, Faculty of Health Sciences

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