ABSTRACT Introduction Chronic pain affects 1 in 5 adults and children globally; however, management remains highly variable and low value care is common. Inconsistent recommendations among clinical practice guidelines for management of chronic pain contribute to suboptimal patient management. We will develop and disseminate a living digital chronic pain recommendation map (e‐Chronic Pain RecMap) to identify trustworthy recommendations in three high priority areas, (1) opioids, (2) cannabis for medical purposes, and (3) spine‐related interventional procedures for chronic pain. Methods The project comprises three phases. A planning phase to engage a diverse group of interest holders to co‐design a team structure with our knowledge users to ensure an efficient and effective workflow. Through a search of electronic databases and a manual search of international websites, a development phase to systematically identify relevant guidelines published in any language since 2019. In this development phase, we will update our searches every 6 months. Also, we will appraise the reporting quality of eligible guidelines using the AGREE‐II instrument, followed by appraisal of recommendation‐level quality using AGREE‐REX for guidelines meeting a defined threshold. In a next step, we will extract data from guidelines including relevant equity information using infrastructure in GRADEPro, and explore divergence and compare recommendations answering the same guideline question. Lastly, we will develop plain language summaries of trustworthy recommendations and decision aids to support patient‐physician decision making, and translate the platform to French, Spanish, and Mandarin. Finally, a mobilization phase in which, with our interest holders, we will co‐create strategies to disseminate the RecMap to relevant target users. Discussion The Chronic Pain RecMap will enhance use of trustworthy guideline recommendations by people living with chronic pain, clinicians, and decision makers. Successful uptake will optimize evidence‐based pain management.
Summary What is already known on this topic? Chronic pain is a common condition affecting 1 in 5 adults and children globally. Hundreds of clinical practice guidelines have been developed to optimize practice but vary widely in quality and often present inconsistent recommendations. There is an urgent need to increase chronic pain literacy across healthcare systems and among the public at large, and improve concordance between evidence and practice. What this study adds? A plan to co‐design and develop a living digital chronic pain recommendation map. Methods to consolidate, systematically appraise and compare guideline recommendations in three high‐priority areas for chronic pain including opioids, cannabis and spine‐rated interventional procedures. A plan to translate and mobilize knowledge from the RecMap based on co‐creation with national and international collaborators and interest holders.