Experts has a new look! Let us know what you think of the updates.

Provide feedback
Home
Scholarly Works
Efficacy and safety of thrombolysis for pediatric...
Journal article

Efficacy and safety of thrombolysis for pediatric venous thromboembolism: a systematic review and meta-analysis

Abstract

ABSTRACT: We conducted this systematic review to evaluate outcomes of thrombolysis followed by anticoagulation vs anticoagulation alone in pediatric patients with venous thromboembolism (VTE). This systematic review addresses mortality, VTE resolution, recurrence, bleeding, and organ-specific outcomes in 5 PICO (population, intervention, comparison, outcomes) questions on thrombolysis across pulmonary embolism (PE), extremity deep vein …

Authors

Kawtharany H; Azzam M; Alkhader A; Betensky M; Hamarsha Q; Abou Zeid HK; Mansour R; Tabak C; Patel P; Baghdadi SL

Journal

Blood Advances, Vol. 9, No. 21, pp. 5512–5527

Publisher

American Society of Hematology

Publication Date

November 11, 2025

DOI

10.1182/bloodadvances.2025017058

ISSN

2473-9529