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Systematic Review: Efficacy of Medical Therapy on...
Journal article

Systematic Review: Efficacy of Medical Therapy on Outcomes Important to Pediatric Patients With X-Linked Hypophosphatemia

Abstract

OBJECTIVE: To examine the evidence addressing the management of X-linked hypophosphatemia (XLH) in children to inform treatment recommendations. METHODS: We searched Embase, MEDLINE, Web of Science, and Cochrane Central up to May 2023. Eligible studies included randomized controlled trials (RCTs) and observational studies of individuals younger than 18 years with clinically or genetically confirmed XLH. Manuscripts comparing burosumab to either …

Authors

Ali DS; Mirza RD; Hussein S; Alsarraf F; Alexander RT; Abu Alrob H; Appelman-Dijkstra NM; Biosse-Duplan M; Brandi ML; Carpenter TO

Journal

The Journal of Clinical Endocrinology & Metabolism, Vol. 110, No. 5, pp. 1205–1217

Publisher

The Endocrine Society

Publication Date

April 22, 2025

DOI

10.1210/clinem/dgaf011

ISSN

0021-972X