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Structure of human phosphatidylcholine transfer...
Journal article

Structure of human phosphatidylcholine transfer protein in complex with its ligand

Abstract

Phosphatidylcholines (PtdChos) comprise the most common phospholipid class in eukaryotic cells. In mammalian cells, these insoluble molecules are transferred between membranes by a highly specific phosphatidylcholine transfer protein (PC-TP) belonging to the steroidogenic acute regulatory protein related transfer (START) domain superfamily of hydrophobic ligand-binding proteins. The crystal structures of human PC-TP in complex with …

Authors

Roderick SL; Chan WW; Agate DS; Olsen LR; Vetting MW; Rajashankar KR; Cohen DE

Journal

Nature Structural & Molecular Biology, Vol. 9, No. 7, pp. 507–511

Publisher

Springer Nature

Publication Date

July 2002

DOI

10.1038/nsb812

ISSN

1545-9993