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Monumental-6: A Phase 3 Study of Talquetamab +...
Journal article

Monumental-6: A Phase 3 Study of Talquetamab + Pomalidomide or Talquetamab + Teclistamab Vs Elotuzumab + Pomalidomide + Dexamethasone (EPd) or Pomalidomide + Bortezomib + Dexamethasone (PVd) in Patients with Relapsed/Refractory Multiple Myeloma Who Received 1-4 Prior Lines of Therapy, Including Lenalidomide and an Anti-CD38 Monoclonal Antibody

Abstract

Background:Patients (pts) with multiple myeloma (MM) often receive immunomodulatory drugs (IMiDs; eg, lenalidomide), proteasome inhibitors (eg, bortezomib), and anti-CD38 monoclonal antibodies (mAbs) as part of their initial treatment. However, most pts relapse following initial treatment, with increasing attrition rates observed at each subsequent line of therapy (LOT), creating an unmet need for treatment options for pts with …

Authors

Nooka AK; Mian H; Lee C; Rodríguez-Otero P; Kumar S; Einsele H; Vishwamitra D; Vieyra D; Kane C; Kosh M

Journal

Blood, Vol. 144, No. Supplement 1,

Publisher

American Society of Hematology

Publication Date

November 5, 2024

DOI

10.1182/blood-2024-199752

ISSN

0006-4971